Over time, in-can preservatives have evolved in the direction of more selective toxicity. Mercury based biocides represent the first generation. While these compounds were highly effective against microorganisms, they also had significant toxicity to higher forms of life, and they have now largely been regulated out of use. Formaldehyde and formaldehyde mechanisms biocides found favor as replacements for mercury based biocides, and they represent the second generation. Over time, and to varying degrees, these compounds have also encountered regulatory pressure and many of their uses have now been restricted. As formaldehyde mechanism biocides came under pressure, isothiazolinone biocides grew in popularity. These biocides represent the third generation. It is inevitable that there will be a fourth generation of in-can preservatives, and some regulatory pressures on isothiazolinones are already emerging. This presentation reviews emerging regulatory trends, and describes some potential future directions and technologies for in-can preservation.
Scott Brown leads Lonza’s Materials Performance and Protection Global Applications Technology group. This group is responsible for providing applications support for existing biocide products of the Materials Protection business, and for guiding the development effort for new biocide products.